For clindamycin, the cases with the reported adverse outcome of death were for the treatment of cerebral toxoplasmosis (2 [15%] out of 13 cases) or toxoplasmosis
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successful treatment single clindamycin in cerebral toxoplasmo-sis HIV
Because of its good intestinal absorption, oral and parenteral dosages are similar
It is a relatively common disease that is found worldwide in animals, birds, and even humans
gondii by an unknown mechanism that may involve the pathogen organelle apicoplast
Infection occurs after ingestion of bradyzoite cysts in the tissues of intermediate vertebrate hosts resulting in patent infections in 97% of naïve cats
Purpose: To report a case series of four ocular toxoplasmosis patients who received intravitreal clindamycin as first-line treatment
1 ml) followed by prompt initiation of oral antibiotics (see below) as well as topical anti-inflammatory and cycloplegic agents
Toxoplasmosis is caused by the intracellular coccidian Toxoplasma gondii
For clindamycin, the cases with the reported adverse outcome of death were for the treatment of cerebral toxoplasmosis (2 [15%] out of 13 cases) or toxoplasmosis (11 [85%] of 13 cases; Fig
Cats can rarely contract clinical toxoplasmosis, but it is more common for the parasite to lay dormant in cats and spread to other animals without creating any symptoms of illness in the cat itself
Toxoplasmosis is a widespread zoonosis, which may have an important impact on human and animal health worldwide Clindamycin, azithromycin and atovaquone are alternative treatments when PYR/SDZ or TMP/SMX cannot be used, despite the lack of randomized studies to support their use
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Trimethoprim Cerebral toxoplasmosis related to AIDS was treated with a combination regimen of pyrimethamine, clindamycin, and spiramycin, and in a second trial with a combination of pyrimethamine and clindamycin
The most commonly used combinations are clindamycin and corticosteroids, and pyrimethamine